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Q. How is ISORelief™ different from other natural pain relief products—Aren’t all natural solutions the same—safe, natural and effective?
A. Most botanical inflammatory controlling compounds from the plant kingdom have low bioavailability and lack potency. These natural alternatives are ineffective. IsoRelief was clinically tested alongside 20 other botanicals for pain relief, and found to be at least 20 times more potent than any other botanical tested for minor pain relief!*
Q. How can something natural work so well?
A. ISORelief is all-natural. Yet this remarkable breakthrough has been    formulated to deliver maximum strength relief. Extensive human oral dosing  studies show ISORelief to be equivalent in effectiveness to over-the-counter (OTC) and prescription drugs for reducing minor pain.  
Q. Why should ISORelief work for me?
A. Because it does something nothing else does—eases headache and muscle pain  by delivering minor pain relief to all seven biochemical systems that cause pain in the body, yet in a gentle balanced way. And although individual results may vary, ISORelief has been clinically proven to give you fast relief—and more of it!
Q. Why haven’t I heard of these seven major pain-causing biochemical systems?
A. For decades doctors and scientists have been trying to solve the problem of pain  as if they were shooting it with a rifle—only focusing on one target center—which in this case has been the COX-2 enzyme. But there is a whole constellation of pain-causing biochemicals discovered that cause minor pain in the body: 1.Cyclooxygenase (Cox 2), 2. Lipooxygenase (5-Lox), 3. Iso-P (Isoprostane),  4.NF Kappa B, 5. TNF-µ, 6. iNOS (inducible nitric oxide synthase),  7. RNS (Reactive Nitrogen Species).
Q. Is ISORelief safe to take with my other supplements or medications?
A. Yes, it is although you should not take it if you are pregnant.
Q. If I have a sensitive stomach can I take this without problems?
A. Fast-acting, natural prescription strength ISORelief can be taken everyday without any stomach upset.
Q. If my pain is severe can I take more than the recommended daily amount?
A. ISORelief is a maximum strength pain reliever and the recommended dosage even for severe pain is 2-caplets 2 times daily.
Q. Can ISORelief work well in conjunction to taking other natural products for pain relief such as Glucosamine?
A. Glucosamine, Chondroitan, MSM, SAMe etc. can renew cartilage and improve mobility over longer periods of time, but they’re slower at relieving joint and muscle discomfort. If you have painful joints and muscles you want fast relief!    

Along with providing rapid minor pain relief, ISORelief also helps to nourish and  rebuild cartilage, increase bone density and enhance joint mobility. 

Not only is ISORelief far more potent than all the natural botanical products  tested, but studies prove it is clearly comparable in efficacy to the popular over-the-counter  and prescription products. And the greatest advantage is; ISORelief has a stomach friendly  side-effect profile with no reported negative effect on cardiovascular health!    

It is a full spectrum pain relief product—one that works rapidly, can be taken everyday without any stomach upset and helps to nourish and rebuild cartilage, increase bone density and enhance joint mobility. ISORelief keeps working  even after the pain is gone!

Q. Is there any science behind ISORelief?
A. ISORelief was studied at the William Harvey Institute, St. Bartholomew's  Medical College at the Royal London School of Medicine. The William Harvey Whole Blood Assay is now considered the gold standard for measuring Prostaglandin E-2 (PGE-2) activity. Results from screening the majority of non-steroidal anti-inflammatory drugs  (NSAID’s) aspirin, ibuprofen, and naproxen and COX-2 prescription drugs like Vioxx and Celebrex have been published using this protocol by Warner et al in Proc. Natl. Acad. Sci. Vol. 96, pp7563-7568, 1999. Two human oral dosing clinical studies were performed on ISORelief. 

These studies were designed to assess the Prostaglandin E-2 (PGE-2) inhibition of ISORelief in vivo (in human blood). The two most important things that need to be determined when screening for new PGE-2 anti-inflammatory compounds are the potency and selectivity.

ISORelief had a PGE-2 inhibitory potency comparable to that obtained from a single 2-tablet dose of Ibuprofen, while possessing superior selectivity.* 

Comparison of data from a validation study suggests that ISORelief would provide PGE-2 inhibitory potency comparable or better than a single dose of Celebrex, with superior selectivity. The present study suggests that ISORelief is clearly a selective and potent PGE-2 inhibitor, comparable to Ibuprofen and Celebrex in efficacy, but with superior selectivity for Prostaglandin E-2. The better the selectivity for PGE-2, the less gastric side-effects.

*
Clinical results published in the medical journal: Inflammation Research v. 52 sup. 2 page 2-123
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